연구실

의과학관 111호

Research profile

교수소개

As a medical statistician she is specialized in research methodologies for evidence based medicine. Her expertise lies in clinical trials: design and conduct of clinical trials as well as a meta-analysis of clinical trials, and cost-effectiveness analysis alongside clinical trials. She also has a particular interest in methods for design and conduct of systematic reviews. She is currently taking the leadership of the Medical Statistics Division within the Medical Research Collaborating Center and her team is involved with various collaborative clinical researches and also research with the public health sectors.

연구실

의과학관 106호

Research profile

학력

• 1999. 약학사, 이화여자대학교 약학대학 약학과
• 2004. 의학박사, 서울대학교 대학원 의학과(예방의학/분자역학 전공)
• 2005. - 2008. 미국 로즈웰파크 암연구소 박사 후 연구원
• 2008. - 2011. 인제대학교 약물유전체연구센터 전임강사
• 2011. - 현재 서울대학교 의과대학 부교수

전공분야

Molecular epidemiology, biomarker, gene-environment interaction, pharmacogenomics, high-risk cohort

연구분야

전통적인 역학연구는 인구집단에서 복합 질병의 원인에 관한 요인을 밝혀내는데 많은 역할을 해왔다. 이를 확장하여 본 연구실에서는 설문에 의한 정보 수집 이외에 여러 가지 생체지표를 이용한 분자역학 방법론을 통하여 질병의 원인과 예방 및 치료에 대한 연구를 수행하고자 한다. 역학의 개념과 방법론, 생체 지표의 개념과 종류, 그에 따른 분석 방법론, 통계학적 지식 등 관련 분야의 전반적인 개념을 이해하여 다음과 같은 연구를 수행하고 있다. - 환자-대조군 및 코호트의 대규모 일반 인구 집단에서 암 및 만성 질환의 감수성을 예측, 생체 지표의 개발, 특히 생활습관 및 식이와 같은 환경적 요인에 따라 변화하는 개인의 감수성으로서 질병의 위험도를 평가함. - 중개 연구로서 질병의 예후 및 효과적인 약물 치료 반응을 예측할 수 있는 생체 지표 개발과 타당성 검증함.

최근연구업적

1. Heterogeneity of epidemiological factors by breast tumor subtypes in Korean women: a case-case study. Int J Cancer, 2014 (in press)
2. Association between chronological change of reproductive factors and breast cancer risk defined by hormone receptor status: results from the Seoul Breast Cancer Study. Breast Cancer Res Treat, 2013
3. Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls. Hum Mol Genet, 2013
4. A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study. Breast Cancer Res, 2012
5. Genome-wide association study in East Asians identifies novel susceptibility loci for breast cancer. PLoS Genet. 2012
6. Nitric oxide synthase variants and disease-free survival among treated and untreated breast cancer patients in a Southwest Oncology Group Clinical Trial, Clin Cancer Res, 2009

교수소개

Dr. Choi joined the SNU faculty in 2011. Formerly, she was a member of the Department of Cancer Prevention and Control in Roswell Park Cancer Institute in NY, USA until 2008 when she joined the faculty at Pharmacogenomic Research Center in Inje University. She is currently the assistant professor of College of Medicine. Dr. Choi graduated from Ewha Woman’s University College of Pharmacy and earned her PhD degree at Seoul National University in 2004. She is a molecular epidemiologist with background and expertise in the role of gene and environmental interaction associated with the etiology of cancer and the survival.
Research Interests:
- Molecular cancer epidemiology especially for hormone-related cancer
- Pharmacogenomic epidemiology
- Dynamic biomarkers to predict development of cancer and the treatment outcome

Research profile

Research profile

최근연구업적

https://publichealth.ku.dk/staff/?pure=en%2Fpersons%2Fyounhee-lim(98ec27d1-dda4-446b-8be1-8bc52fcb8bed)%2Fpublications.html

교수소개

I am an Assistant Professor at the Department of Public Health, University of Copenhagen in Denmark and an adjunct professor at the Department of Preventive Medicine, Seoul National University College of Medicine.

My principal area of interest is to estimate environmental effects on health using big data. I investigate the effects of air pollution, noise, and climate on cardiovascular diseases and psychiatric disorders in the population by linking the register-based health and historical exposure data. I am also involved in several cohort studies of children, women, and the elderly. I examine the effects of air pollution and endocrine disrupting chemicals on growth and neurocognitive development in children and cardiovascular, metabolic, and neurodegenerative diseases in women and the elderly. In addition, I am interested in the roles of the gene, DNA methylation, and microbiome on environmental health.

Research profile

학력

• 서울대학교 의과대학 졸업(의학사)
• 서울대학교 의과대학 대학원 졸업(의학석사)
• 서울대학교 의과대학 대학원 예방의학 박사수료

주요경력

• 서울대학교 의과대학 직업환경의학 전공의
• 서울서부 근로자건강센터 센터장
• 서울특별시 보라매병원 종한건강진단센터 조교수
• 서울특별시 보라매병원 공공의학과 조교수

전공분야

직업환경의학, 환경역학, 직업역학